Akkouh, Ibrahim Ahmed; Ueland, Thor; Szabo, Attila; Hughes, Timothy; Smeland, Olav Bjerkehagen; Andreassen, Ole; Requena Osete, Jordi; Djurovic, Srdjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-03)
BACKGROUND: Schizophrenia (SCZ) has a known neurodevelopmental etiology, but limited access to human
prenatal brain tissue hampers the investigation of basic disease mechanisms in early brain development. Here, we
elucidate the molecular mechanisms contributing to SCZ risk in a disease-relevant model of the prenatal human brain.<p>
<p>METHODS: We generated induced pluripotent stem cell–derived ...